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This sensor is based on binding of a spirocyclic SiR ligand to HT, which induces isomerization to the GSH-sensitive and fluorescent zwitterionic form

Ex-vivo approaches

At the onset of the protocol, the MMN of patients was significantly impaired compared to sex- and age- matched healthy controls ( p =0.003), without any evidence of concomitant P300 component deficits

Relative to cell growth and death and aging, ferroptosis had the highest enrichment score (Additional file 2: Figure S1)

Cell Stem Cell 28 , 18221837.e1810 (2021)

Lean proteins provide the amino acids necessary for the body to build its own antioxidant defenses