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76,77 In summary, disc cells respond to altered loads and osmotic pressures, to DAMPs, MMPs and pro-inflammatory cytokines with the expression of catabolic enzymes, with anabolic healing attempts, and with inflammation resulting in failed healing attempts, damage accumulation and chronic inflammation leading eventually to DD

Gonzalez- Rivas PA, Chambers M, Liu J

Oral peptides bypass the injection entirely but may have different bioavailability and primary effects compared to their injectable counterparts

They also include loads of carbohydrates, which can cause high blood sugar spikes and may harm adrenal function

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Extended exposure above 8C accelerates degradation