Xu Q, Cheng D, Li G, Liu Y, Li P, Sun W, et al
10.3892/ijmm.2017.3255 103 LudtmannM
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GLP1R is expressed in pancreatic cells and the nervous system, and mediate the effects of GLP-1 in regulating glucose homeostasis through multiple mechanisms including direct actions on the endocrine pancreas and indirect activation of central nervous system controlling gastric emptying, satiety, and body weight
Li T, Jiao JJ, Hlscher C, Wu MN, Zhang J, Tong JQ, et al
For instance, depletion of mGSH results in Trx2 oxidation (Zhang et al., 2007), while hypercholesterolemic pigs with selective depletion of mGSH in heart mitochondria, exhibit decreased levels of the mitochondria-specific antioxidant enzymes such as SOD2, Trx2, and Prx3 (McCommis et al., 2011)