For example, certain anti-cancer therapies like radiotherapy and some chemotherapy drugs could produce oxidative stress in tumor cells by increasing ROS components and induce tumor cell death
Collagen peptide supplements are typically sourced from: Bovine collagen Marine collagen They are commonly available as powders that dissolve easily into coffee, smoothies, or water
Indeed, selective activation of PGC-1 within the hepatocytes protects the liver from lipids overload and progression to fibrosis, due to its ability to induce mitochondrial oxidative phosphorylation, fatty acids -oxidation and citrate cycle, while decreasing oxidative stress and promoting triglycerides excretion in the bloodstream 15
These therapies display higher efficiency compared to classical senolytic drugs (BCL-2 or tyrosine kinase inhibitors) but for some of them, such as NA + /K + ATPase inhibitors, clinical development could be complex in the light of strong cardiotoxicity associated with this class of molecules
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Inter J Food Sci Nutr 73:10471056