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GLP-1 agonists regulate both appetite and blood sugar in ways that can significantly aid weight loss, particularly in individuals with obesity

While certain supplements may support wellness, they should never replace medical guidance

In a phase 1b trial, 20 weeks of cagrilintide 2.4 mg once weekly in combination with semaglutide 2.4 mg once weekly (cagrisema) resulted in up to 17.1% WL compared to 9.5% WL with semaglutide 2.4 mg plus placebo in people with obesity [88]

Women of childbearing potential must use effective contraception during treatment and add non-hormonal backup contraception for 4 weeks when initiating or increasing tirzepatide doses due to potential decreased oral contraceptive effectiveness

If appetite reduction leads to inadequate protein consumption, muscle loss will be more pronounced

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