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Lilly has announced recruitment for a tirzepatide trial in people with type 1
The clinical evidence base for these two compounds differs substantially in maturity, scope, and regulatory recognition
Because data shows that women experience nausea and vomiting at up to 2.5 times the rate of men while on GLP-1 agonists (possibly due to higher GLP-1 receptor expression in female brain regions associated with nausea), microdosing GLP-1 medications could potentially help lower the likelihood of these effects
The 12 mg dose produced a mean weight change of negative 23.7%, translating to roughly 60 pounds of weight loss
Presented for research literature review only Xie PY et al
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Biology, 12(7), 973
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