In one 2024 real-world study, 40% of GLP-1 patients had inadequate protein intake, and 25% had suboptimal vitamin D, B12, iron, or calcium within 3 months of starting therapy
On the other hand, the risks of HHF (HR 0.93, 95% CI 0.831.04 with GLP-1RAs and HR 0.69, 95% CI 0.610.79 with SGLT2is) and composite kidney outcomes excluding macroalbuminuria (HR 0.92, 95% CI 0.801.06 with GLP-1RAs and HR 0.55, 95% CI 0.480.64 with SGLT2is) significantly reduced with SGLT2is only
If those results are positive (and the TRIUMPH-4 data strongly suggests they will be), Eli Lilly would then file a New Drug Application with the FDA
Robert, 1979
The medicine works by sending signals to the appetite center in your brain to reduce hunger
GI-related adverse events were most prevalent during the first week of treatment, with observed rates generally declining through the remainder of the study