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When determining the Alanine to Lysine ratio as an indirect measure of mitochondrial distress we found that unaffected children had an average ratio of 5.8 and those with konzo have an average ratio of 6.9, both of which are substantially higher than the expected ratio of less than 3 for healthy adolescents (Fig

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Aggregates are also a known immunogenicity risk, meaning they can trigger antibody formation that reduces drug effectiveness over time and rarely causes injection-site reactions

His innovative idea introduced a way to deliver essential vitamins and minerals directly into the bloodstream, bypassing the digestive system for faster and more effective results

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