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The molecular events leading to activation or silencing of glucose-sensitive neurons are surprisingly similar to those of the endocrine pancreas and include neuronal uptake of glucose via GLUT2, conversion to pyruvate (and finally ATP) via glucokinase, and modulation of neuronal firing mediated by changes in K ATP channel activity, cell depolarisation and Ca 2+ influx
Subjects with diabetes were excluded
FSH elevations promote androgen aromatization to estrogens in the Granulosa cells, a process which contributes mainly to folliculogenesis and oocyte maturation [43]
By setting realistic expectations and personalising the care plan, GPs can help patients manage this common skin condition, improving their skin health and quality of life
