how was semaglutide discovered 30 years of obesity research and over 100 years of medical breakthroughs. Learn more about and the story behind the discovery here: https://lnkd.in/e_as9aKV | Novo Nordisk From Diabetes to Weight Loss

If your weight plateaus for several months while on a stable dose, it might be time to revisit your strategy with your provider

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Individuals with a BMI of 25-29.9 may be a candidate if they have obesity related conditions such as high cholesterol, hypertension, etc

28.2% in controls) Improved collagen organization and increased deposition Enhanced glutathione levels and antioxidant enzyme activity Increased angiogenesis through VEGF and FGF-2 stimulation Reduced pro-inflammatory markers (TNF-, IL-6) with decreased NF-B signaling Fibroblast migration stimulation and extracellular matrix remodeling GHK-Cu research consistently demonstrates that the peptide is biologically active at very low concentrations in the nanomolar range (110 nM)

While these effects may be beneficial in selected cardiovascular indications, they raised concerns regarding hypotension and hemodynamic instability when considered for chronic metabolic disease