Additionally, dimethyl fumarate (DMF) and its metabolite monomethyl fumarate (MMF) show a neuroprotective effect on oxidative stress and could relieve OXA-induced neurite degenerations via activating the Nrf2 pathway in PC12 cell lines (Kawashiri et al., 2018)
Pruritus, another distressing symptom, is managed with moisturizers and antihistamines, though many treatments show limited success
10.1016/j.biopsych.2003.10.006 Biol
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