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Synergistic interactions between growth hormonereleasing hormone and secretagogues in experimental models. Journal of Neuroendocrinology

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The drug excretes ~280 kcal/day through urine a dietary deficit of a further 200300 kcal/day through portion control can double the effective calorie deficit without requiring dramatic dietary changes

GHK-Cu Gene Regulation Pickart et al

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These medications fall under a class known as glucagon-like-peptide-1 receptor agonists also known as GLP-1s