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In a Swiss study (11), almost half of all general practitioners agreed with prescribing B12 for unexplained fatigue, even though theres not much research to bear it out

It has a well-understood mechanism with a growing body of long-term safety data

Improved Mood and Mental Clarity: B12 helps regulate serotonin production, a neurotransmitter that influences mood, memory, and focus

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The difference between the two is that intramuscular injections are inserted into the muscle, and subcutaneous injections are inserted just below the skin

Response timing varies