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10.1210/clinem/dgab408 J Clin Endocrinol Metab

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The researchers even did brain scans and concluded that being unknowingly slipped about 200 mg of quinine not only affected how much the study participants felt like they wanted to eat, but how much they actually did eat, by interfering with reward brain circuits

Participants receiving 2.4 mg of Sema weekly, alongside lifestyle modifications, experienced an average 14.9% reduction in body weight over 68 weekssubstantially more than the placebo group

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