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However, as with many medications, there are potential side effects

Methods Reagents and animals Male C57BL/6J mice, aged 4 weeks and weighing approximately 1820 g, were obtained from Beijing Vital River Laboratory Animal Technology

Cohen O, Gillam M

The Journal of Nutrition , vol

Contact your healthcare provider if you experience: Signs of hypothyroidism : increased fatigue, cold intolerance, constipation, weight gain despite semaglutide, depression, or cognitive changes Signs of hyperthyroidism : anxiety, tremor, palpitations, heat intolerance, unexplained weight loss beyond expected, or insomnia Severe gastrointestinal symptoms : persistent nausea, vomiting, or diarrhea that might affect medication absorption Hypoglycemia symptoms : shakiness, sweating, confusion, or dizziness (particularly if also taking insulin or sulfonylureas) Maintain a consistent schedule for taking levothyroxineideally at the same time each day

Serious adverse events are rare when protocols are supervised and contraindications are respected