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The speed depends on how much your eating habits actually changed during treatment and your individual genetic factors that control appetite regulation
Tolerance and digestive effects Common comments include issues of gastrointestinal tolerance (discomfort, nausea, diarrhoea) and, at high doses, the possible characteristic body odour described in some sources
Known LES relaxants
A 2025 study of high dose semaglutide injection (7.2 mg) showed that adults with obesity lost around 21% of their body weight after 72 weeks
It acts on three metabolic receptors simultaneously GLP-1, GIP, and glucagon through a single molecule
Ethics statement The animal study was reviewed and approved by Kanazawa University Animal Experiment Committee
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