You may not need traditional surgery
The total human evidence base, as of this writing, consists of the following: 1) a Phase I safety trial of 42 healthy volunteers that was registered in 2015, canceled in 2016, and never published, 2) a retrospective case series of 12 patients with knee pain, no control group, and no validated outcome measure, and 3) a 2025 pilot safety study involving two healthy adults who received intravenous infusions at a single private clinic in Florida
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In drug-induced pyridoxine deficiency, such as in patients taking isoniazid, a higher replacement dose is often used, for example, 100 mg IV or IM daily for 3 weeks, to rapidly correct the deficiency, followed by a maintenance dose of around 30 mg daily
Another official was even blunter, saying the agency does not know with any certainty what the substance is
Always use gentle swirling motions instead