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November 2025: FDA approved expanded Zepbound (tirzepatide) indication for moderate-to-severe obstructive sleep apnea in adults with obesity, following SURMOUNT-OSA trial data showing 62.8% reduction in apnea-hypopnea index the first drug approval for sleep apnea treatment

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The mean concentrations of prolactin, TT, LH, and FSH were 8.8 ng/ml, 13.3 ng/dL, 7.2 IU/L, and 9.7 IU/L, respectively

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HR = 0.87

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