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One analogy you could look at is cancer treatments
B12 Deficiency Correction: Weekly For confirmed B12 deficiency or pernicious anemia: weekly injections for 48 weeks to saturate body stores, then monthly maintenance
Ugleholdt, R
Deficiencies can be caused by genetic disorders, malnutrition, malabsorption and kidney dialysis, and affect the heart, skeletal muscles, liver, nerve, and endocrine functions
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