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Integrative Medicine: A Clinician's Journal, 13 (1), 8

For medical purposes, some doctors may recommend a weekly B12 shot for up to four weeks

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These unstable oxygen molecules are missing an electron, so they rip electrons from their neighbors, creating more free radicals

Summary: Vitamin B12 treatment typically begins producing early haematological responses within 34 days, with neurological symptoms starting to improve within 12 weeks, though complete symptom resolution may require several weeks to months depending on deficiency severity and treatment route