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NNMT as Target (Kraus et al., 2014): NNMT knockdown in white adipose tissue and liver protected against diet-induced obesity by increasing cellular energy expenditure
MOTS-c enhances memory formation and protects against neuroinflammation, with benefits observed in Alzheimers and metabolic dysfunction models [6]
Researchers engineered it with an added N-terminal tyrosine for stability, with one goal: isolate the fat-mobilising part of growth hormone while leaving out the rest of the hormonal cascade
Use within 28 days of reconstitution, and discard the vial if the solution becomes cloudy, loses its blue tint, or develops particles
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