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Laberge RM, Sun Y, Orjalo AV, Patil CK, Freund A, Zhou L et al
Fatty acid conjugation as used in Semaglutide and Retatrutide promotes reversible albumin binding that shields the peptide from enzymatic degradation and slows renal filtration, extending the half-life from minutes to days
This function is impaired when glutathione levels are low
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Cell Res 1866 , 14331449 (2019)
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