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The 5-foot-7 fashion startup founder first went on a GLP-1 when her weight was fluctuating from 130 to 150 pounds, which at her heaviest would put her BMI at 23.5 considered in the healthy weight category
However, there is limited experience in patients with severe hepatic impairment, and these medications should be used with caution in such cases, preferably with specialist input
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While cardiovascular death alone didn't reach statistical significance (middle-left panel), consistent directional benefits appeared across heart failure outcomes and all-cause mortality, suggesting broad cardiovascular protection
Individuals carrying specific FTO or MC4R variants may experience sharper metabolic shifts that can trigger temporary anxiety as their bodies adapt to improved glucose control and appetite suppression
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