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Many cases of apparent treatment failure turn out to be dosing errors
In select cases particularly patients with: Obesity High insulin resistance Very high total daily insulin requirements endocrinologists may consider off-label use with: Continuous glucose monitoring Routine ketone monitoring Strict sick-day protocols Close specialist follow-up But this is not standard therapy
Bonhaus DW, et al
Third, we examined a cohort excluding individuals with kidney disease, previous pancreatitis, or previous falls
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& Lunde, I
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