Therefore, we recommend tumor-specific assessment, integrating systemic iron indices with tumor and TME iron-handling markers and immune phenotype, to guide iron-targeted interventions in cancer patients
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Additionally, the spinal cord contains high levels of PUFAs, which are prone to oxidation following SCI, providing a basis for iron-dependent lipid peroxidation and promoting ferroptosis (Baazm et al., 2021)
Preventing bone diseases Age-related bone disorders like osteoporosis result from an imbalance between osteoclastic and osteoblastic activity