Side effects of the exenatide brands Exenatide shares the class side-effect profile, and nausea is reported particularly often with the twice-daily form: Nausea, most common when starting or after a dose increase Vomiting and diarrhea Reduced appetite Injection-site reactions, including small nodules that are more frequent with the extended-release product Pancreatitis is a labeled risk for the class
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Some people still report feeling better after a shot, but that can reflect many factors (sleep, stress, expectations, hydration, or other changes)