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49 This stage has the highest risk of mortality, which is most frequently due to multi-organ failure
To ensure harmonization with the SARP data set, the count data for the IMSA cohort was generated using the same processing pipeline that was used to generate the SARP count data
The data presented here provide evidence in favour of altered mitochondrial metabolism and suppression of anabolism being major consequences of toxic doses of APAP in HepG2 cells, and that resulting lactic acidosis may be contributing specifically to cell death
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