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introduced a pioneering hierarchical nano-in-micro delivery platform wherein doxorubicin-loaded chitosan nanoparticles were integrated into biodegradable PLGA microspheres to fabricate subcutaneous implants, representing the first application of this architecture for sustained regional chemotherapy in breast cancer models

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Nestin is found in several cell subsets, such as neural stem and progenitor cells, glia, mesenchymal stromal cells, endothelial cells and Schwann cell precursors in the peripheral nervous system 42