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While the full appetite-suppressing effects are still being validated, this innovation signals growing interest in meal-embedded satiety solutions

American Society of Anesthesiologists

Some agents (Wegovy, Saxenda) are also approved for weight management in adolescents aged 12 and older

The ASTRAAS trial (NCT04714320) evaluated changes in SBP from baseline to day 85 as the primary endpoint, whereas the ASTRAAS-HF trial (NCT04836182) investigated whether IONIS-AGT-LRx could serve as an adjunct therapy to standard treatment in patients with HFrEF

[13] Treatment was given for 30 weeks