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These effects are largely attributable to the GLP-1 receptor agonist component of the drug, which slows gastric emptying and alters gut motility

95% CI, 0.08 to 4.21) [79]

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That could shift over time

it is not known if they will cause thyroid tumors or cancer in humans

Typically, these factors are used to estimate a patient's risk of developing cardiovascular disease in the next 10 years