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Neurosci Lett 192: 1316

Anecdotal reports suggest any blood pressure effects are most noticeable in the first one to two weeks of BPC-157 use, then diminish as the body adapts

The caveat is uniform and important: a mechanistic effect observed in a rat gastric cell assay does not prove the same effect will occur in a human tendon after nasal inhalation

Insurance coverage will be a challenge if not expanded to include other conditions, one physician said, so FDA approval is paramount. This challenge echoes concerns of patients, who also list high costs as the primary obstacle to GLP-1RA treatment, according to The Cure GLP-1RA Report: Insights from Patients on GLP-1RA Medications and the Future of Obesity Treatment, which reports results of a survey of patients who had taken GLP-1RA medications

testosterone, growth hormone, IGF-1) can increase lean mass in selected patients, but require specialist oversight and carry safety concerns [73]