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The compound was developed from work on Epithalamin, a mixture of low-molecular-weight peptides extracted from bovine pineal tissue

Another challenge for nose-to-brain drug delivery is the development of appropriate delivery devices, since standard devices are optimized for local effects and therefore deliver only a small amount of drug to the olfactory region [65]

The larger the volume, the finer the resolution

Tendon and ligament injuries show early mobility improvement in weeks 2 to 4 but structural repair takes 3 to 6 months