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Experiments in animals with uniformly labeled 13C-glutamine demonstrated that glutathione was enriched with five 13C atoms, indicating that glutamine is the primary source for glutathione synthesis [11]

We next sought to examine this mitochondrial biogenesis phenotype in whole-tumour ecosystems to ensure that our observations were not linked to a culture phenomenon, as has previously been described for other metabolic reprogramming studies 23

Gastrointestinal Colorectal Cancer Core Committee