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Heres what we know: Dr
Chen et al., 2020
These metabolites may significantly contribute to ACs in vivo efficacy, supporting the view that AC acts as a prodrug whose therapeutic effects are mediated, at least in part, through its microbial transformation products
Cuglievan B, Kantarjian H, Armstrong S, Rubnitz J, Zwaan M, Dinardo C, Cooper T, Pollard J, Kadia T, Guest E, Short N, McCall D, Daver N, Nunez C, Haddad F, Garcia M, Bhalla K, Maiti A, Catueno S, Fiskus W, Gibson A, Roth M, Khazal S, Tewari P, Abbas H, Bourgeois W, Andreeff M , Gruber T, Shukla N, Truong D, Connors J, Joseph Ludwig J, Stutterheim J, Salzer E, Dam KJ, Sasaki K, Mahadeo K, Tasian S, Borthakur G, Dickson S, Faulk K, Jain N, Jabbour E, Meshinchi S, Garcia Manero G, Ravandi F, Stein E, Kolb A, Issa G
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Changes in proliferation and RNA content during induction classification of acute non lymphoblastic leukemia (ANLL) determined by multiparameter flow cytometry
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