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Umweltwiss Schadst Forsch 17(1):5053 Sandermann H (1994) Higher plant metabolism of xenobiotics: the green liver concept
Low-Dose Naltrexone (LDN)-Review of Therapeutic Utilization Karlo Toljan , Bruce Vrooman PMID: 30248938 PMCID: PMC6313374 DOI: 10.3390/medsci6040082 Am J Hosp Palliat Care 2019 Oct;36(10):907-912
Approaches include redox interactions with high-valent metal ions (like Cu 2 and Fe 3 ), suppression of GSH synthesis using agents such as BSO, the use of nanozymes that mimic enzymatic activity, and direct GSH neutralization through molecular binding [18]
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The antioxidant enzyme glutathione peroxidase 3 (GPX3), a ROS scavenger, was first identified as a hub gene in RA neutrophils
