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Especially in the tissues and organs that are susceptible to oxidative stress and inflammation, EGT interestingly maintains a high level (Kato et al., 2010

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Protecting cells from oxidative damage: It safeguards cellular structures such as DNA, proteins, and membranes from damage caused by oxidative stress (NIH)

Lichtenberg J, Perez Calvo E, Madsen K, stergaard Lund T, Kramer Birkved F, van Cauwenberghe S, et al

The nature of the catalytic residue in the EF1B and Ure2p classes is less clear, but RIRT and APNG motifs are found at a position similar to the active site signature in other GSTs