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Adequate protein intake (at least 0.8 to 1.0 grams per pound of body weight), micronutrient supplementation, and gradual dose titration can help minimize this effect

Each enzyme that does the converting requires specific nutrients, called cofactors, including glycine, magnesium, and vitamin B6

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No specific, confirmed DSIP receptor has been identified, making it unusual among characterised neuropeptides

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