J Androl 26:654660
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Among them, 90 UGT genes were expressed in all tissues, accounting for 62.9% of the total UGT genes, while SlUGT3and SlUGT14, which were only expressed in buds, SlUGT53 , SlUGT59 , SlUGT110 , and SlUGT112 , which were only expressed in roots, and SlUGT2 , SlUGT71 were only expressed in fruits
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This Gs-biased profile may contribute to sustained receptor signaling with less desensitization, though the clinical implications of signaling bias in GLP-1 therapeutics remain an area of active investigation