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Further electrophysiological study showed that, opposite to the effects on arcuate POMC neurons, GLP-1 hyperpolarizes arcuate NPY neurons indirectly via increased GABA A receptor-mediated neurotransmission of local GABAergic interneurons (Secher et al., 2014

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By enhancing fatty acid utilization, L-carnitine theoretically promotes greater fat oxidation during exercise and at rest

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