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Studies show side effects can often be reduced by eating smaller meals, avoiding high-fat foods, staying well hydrated, eating slowly, and following a gradual dose increase schedule recommended by a provider
Novel developments in vagal afferent nutrient sensing and its role in energy homeostasis
Many patients find that managing nausea proactivelythrough slow dose escalation and dietary adjustmentsprevents the downstream headache cascade
While previous studies have shown that CNS GABAergic neurons are necessary for the food intake- and body weight-reducing effects of GIPR agonists 5,11 , the anatomic region that underlies these effects remains unknown
It is important to remember that these effects are still being studied, and long-term safety and effectiveness data are not yet complete
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