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The titration schedule increasing the dose gradually allows incretin hormones to stabilize appetite and improve glucose dependent insulinotropic polypeptide activity
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We found that inhibiting ferroptosis effectively delayed fibrosis progression, suggesting that TECs ferroptosis contributes to renal fibrosis
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This hydrophobic side chain allows reversible binding to serum albumin, shielding the peptide from rapid renal clearance and enabling once-weekly dosing
53,54 Fig
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