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Some studies suggest that B12 shots provide a more immediate and potent effect than pills, mainly because the vitamin is injected directly into the bloodstream

Medications- Certain medications, such as proton pump inhibitors and metformin, can interfere with B12 absorption, leading to deficiency over time

It acts as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme expressed in multiple tissues including adipose tissue and the liver that plays a role in cellular energy metabolism and fat storage

So, you know, mission impossible

BioMed Research International, 2015

But in reality, these are often signs of cellular decline, low NAD+ levels , and impaired tissue repair