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In addition, lactylation of pyruvate kinase M2 (PKM2) has been shown to regulate macrophage metabolic reprogramming, driving the transition from pro-inflammatory M1 polarization to pro-fibrotic M2 polarization [104]

Additionally, there was an average improvement in glycated hemoglobin levels of 0.8 point ( 0.6), highlighting the positive impact of the therapy

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Exercise really does get your blood pumping, largely because it improves endothelial function