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Journal Saleem MD, Oussedik E, Picardo M, Schoch JJ
Polymorphisms are also present in GSTs of the alpha class and omega class, with the isoenzymes GSTA1-1, GSTA2-2 and GSTO1-1 and GSTO2, respectively 32
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In addition to being administered as a drug to cause oxidative stress, MTX has also been used to induce cachexia, anorexia, intestinal mucositis and digestive absorption problem in experimental animal models (Reference Boukhettala, Leblond and Claeyssens34Reference Sinno, Coquerel and Boukhettala36)
The most common polymorphisms of GSTM1-1 and GSTT1-1 gene loci consist in the complete deletion of the genes
Administration of Bifidobacterium breve improves the brain function of A1-42-treated mice via the modulation of the gut microbiome
