Moreover, insulin resistance of the adipose tissue, associated with overweight/obesity, contributes to the flux of FFA from adipose tissue to the liver through unrestricted lipolysis ( de novo lipogenesis, i.e., hepatic FFA synthesis, seems to contribute to lipid deposition ( Figure 2 The gut-derived incretin hormones GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) are responsible for the so-called incretin effect (i.e., the potentiation of glucose-stimulated insulin secretion after meal ingestion) ( Glucagon is a key hormone in the regulation of overall energy homeostasis during the fasting state and other energy-demanding situations
For related post-cycle support content, explore our Clomid Guide and Nolvadex Guide
Bibcode:1998MarER..46...71L
doi: 10.3390/nu10101398 57 JiaL.BettersJ
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External resources Glucagon-like peptide-1 receptor agonists for type 2 diabetes - National Institutes of Health Medications containing semaglutide - U.S