They combat free radicals, preventing them from stealing electrons and causing damage to proteins, DNA, and cell membranes
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Autoantibodies and interferon- present in SLE sera enhance binding of the transcriptional repressor CREM to Gpx4 promoter, which leads to suppressed expression of GPX4 and subsequent elevation of lipid-ROS
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The needle will be inserted at a 90 degree angle, which will put the needle deep into the muscular tissue
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