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This FOXO4p53 interaction is essential for maintaining the viability of senescent cells

Wegovy Prescribing Information, revised February 2026

Nardone GP et al

Most individuals will benefit from consuming 1.22.0 grams of protein per kilogram of reference body weight, adjusted for activity level and clinical context

73 Addressing this conflict between reduced appetite and increased protein need is a key element of a successful muscle-sparing strategy on GLP-1 therapy