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J Biotechnol 241:163169
Int J Obes (Lond) (2020) 44(11):217993
If the body doesnt have the nutrients it needs, fewer methyl groups get added to a particular substrate (whether it is DNA, an amino acid, etc.) and the substrate cannot complete its functions as efficiently in the body
Key programs include STEP (14.9% weight loss at 68 weeks in STEP 1), SELECT (20% MACE reduction in 17,604 patients), SUSTAIN (HbA1c reductions up to 2.2%), and PIONEER (oral formulation validation)
Hasson, F., Keeney, S
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