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This is your baseline regulatory safeguard
Semaglutide (single GLP-1 receptor agonist): In the STEP 1 trial, participants on semaglutide 2.4 mg achieved approximately 14.9% body weight reduction at 68 weeks
Maintenance phase
(15) History of stroke, unstable angina, acute coronary syndrome or congestive heart failure New York Heart Association classes III and IV within the preceding 12 months
Tirzepatide at its highest dose produced up to 22.5% in SURMOUNT trials
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