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Of those, 35 were preclinical (animal studies) and one was clinical (human)

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Figure 2: Changes in A) daily food intake, B) weekly food intake, C) daily body weight, and D) overall change in body weight

Studies have shown that when NNMTi is combined with a lowcalorie diet, the rate of body weight loss in obese mice is significantly faster than in either singleintervention group, with more pronounced reduction of adipose tissue and greater improvement in insulin sensitivity and hepatic metabolism

British Journal of Haematology